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KMID : 0388220120190010051
Journal of the Korean Rheumatism Association
2012 Volume.19 No. 1 p.51 ~ p.54
A Case of Refractory SAPHO Syndrome Treated with Etanercept
Kim Ye-Ji

Bae Song-I
Choi Sung-Jae
Lee Young-Ho
Ji Jong-Dae
Song Gwan-Gyu
Abstract
SAPHO syndrome, which has different skin changes and osteoarticular inflammation, is an acronym that stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. Treatment of SAPHO syndrome includes non-steroidal anti-inflammatory drugs (NSAIDs), anti-rheumatic drugs, such as colchicines, corticosteroids and bisphosphonates, and disease-modifying agents. However, the treatment of SAPHO syndrome is controversial because it is a new clinical entity with unclear etiopathogenesis and inadequate clinical studies. We report a case with refractory SAPHO syndrome, which was successfully treated with a tumor necrosis factor (TNF)-? blocker.
KEYWORD
SAPHO syndrome, Treatment, TNF-? blocker
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