KMID : 0388220120190010051
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Journal of the Korean Rheumatism Association 2012 Volume.19 No. 1 p.51 ~ p.54
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A Case of Refractory SAPHO Syndrome Treated with Etanercept
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Kim Ye-Ji
Bae Song-I Choi Sung-Jae Lee Young-Ho Ji Jong-Dae Song Gwan-Gyu
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Abstract
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SAPHO syndrome, which has different skin changes and osteoarticular inflammation, is an acronym that stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. Treatment of SAPHO syndrome includes non-steroidal anti-inflammatory drugs (NSAIDs), anti-rheumatic drugs, such as colchicines, corticosteroids and bisphosphonates, and disease-modifying agents. However, the treatment of SAPHO syndrome is controversial because it is a new clinical entity with unclear etiopathogenesis and inadequate clinical studies. We report a case with refractory SAPHO syndrome, which was successfully treated with a tumor necrosis factor (TNF)-? blocker.
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KEYWORD
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SAPHO syndrome, Treatment, TNF-? blocker
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